What exactly is Methyl Salicylate?

What exactly is Methyl Salicylate?

Therefore, What is Methyl Salicylate? An in depth In Accordance With Menthol

Methyl salicylate is a normal ester that executes very much like menthol. Its commonly extracted through steam distillation of wintergreen leaves.

In accordance with WebMD, methyl salicylate can be found in many topical creams bought throughout the counter for small joint aches or pains that are muscular. It may additionally be present in intimate services and products.

Therefore, what exactly is methyl salicylate and exactly what does it do? Both menthol and methyl salicylate are referred to as counterirritants, meaning they induce cooling and warming feelings on your skin. Counterirritants are primarily Responsible for the true title, and effect, known as “icy hot.”

A lot of these items really should not be applied to younger kids due to poisoning issues, which we’ll discuss later on in this specific article.

Wintergreen Oil

You may nevertheless be wondering, what exactly is methyl salicylate? You will frequently hear about wintergreen oil or “oil of wintergreen.” Relating to a synopsis in the Journal of Alternative Complementary Medicine, methyl salicylate is theprevalent ingredient in the oil and it is the purest kind in the greatest concentration you may find. According to an oil wintergreen podcast through the Royal community of Chemistry, oil of wintergreen contains 96-99% methyl salicylate. Through the source that is same “…research indicates that methyl salicylate is part of a plant’s toolbox when you look at the battle against pathogens and herbivores.”

Methyl salicylate smells extremely strongly of mint. Regardless of this, it must brands of cbd oil additionally be noted that this ingredient will not belong within the mint genus of plant types. The burning sensation that is cold triggered through the TRPA1 channel. Methyl salicylate additionally activates the warmth channel TRPV1, that will be exactly the same channel regarded as activated by hot peppers like capsaicin. Often, wintergreen oil is employed along with peppermint oil, because the two in tandem are considered to attenuate effects that are beneficial. Wintergreen oil is acquired by vapor distillation regarding the warmed, water-macerated leaves. It’s often utilized interchangeably with sweet birch oil for flavoring meals and candies.

Certain Products that Use Methyl Salicylate

Based on drugs.com and goodguide.com, there are several items that have methyl salicylate. Some items include…


Icy Hot Cream

Salonpas Soreness Patch

Analgesic Balm



Menthocin Patch with Lidocaine

Soothee Patch




CVS Mouth Rinse Natural Citrus

CVS Antiseptic Mouth Rinse

K-Y Yours+Mine Partners Lubricant

Jason Natural Cosmetics Dandruff Relief Treatment Shampoo

Forever Residing Aloe Heat Cream

Colgate Peroxyl Antiseptic Oral Cleanser, Original

Orajel PM Toothache cream

CVS Extreme Strength Toothache relief

Young thieves that are living Ultra Toothpaste

Eco-Dent Specialcare Toothpowders Tartarguard

Comparing Methyl Salicylate to Aspirin

One research posted in the Annals of Pharmacotherapy aimed to analyze the efficacy of methyl salicylate in platelet inhibition in comparison to aspirin. Platelet aggregation is another means of discussing platelets clumping together within the bloodstream. This might be associated with blood clotting.

This research utilized a small test of nine healthier males within the 30-46 a long time. All individuals got 162 mg of aspirin before a washout period and then 5 g of 30% methyl preparation that is salicylate both to be utilized to their anterior thighs. It had been unearthed that “both aspirin and MS produced statistically significant platelet inhibition; aspirin decreased the AUC from 183; 139 to 292 to 85; 48 to 128 (p = 0.008) and MS decreased the AUC from 197; 118 to 445 to 112; 88 to 306 (p = 0.011).”

There was clearly no big distinction between the 2. This shows that methyl salicylate works because effortlessly as aspirin for platelet aggregation, at minimum in healthier individuals.

Toxicity Myths and Issues

Research of the substance on the net will reveal a number of case reports of baby death. a few things should be noted about these. Such baby deaths frequently included the accidental swallowing of pure oil of wintergreen, the greatest concentration of methyl salicylate you will get.

This does not imply that overdoses can simply take place with ingestion; the substance may be consumed through skin then incorporated into one’s system. However, it absolutely was present in “Toxicity Myths: the risk that is actual of Acrylic Use,” published into the Global Journal of Aromatherapy, that, “if 10?ml of the 2.5% formula of wintergreen oil had been to be reproduced all at the same time to your epidermis and completely absorbed, the dose would express the exact same level of salicylate present in one single 325?mg aspirin tablet.”

For this reason oil of wintergreen is recognized as to be fairly low-risk with few negative effects. Nonetheless, it is strongly suggested that brand new moms and dads avoid obtaining the substance in the homely household, regarding the off-chance that a child could easily get their or her arms about it.

Additionally, it really is well well worth noting that methyl salicylate happens to be limited for usage in cosmetics in Canada.

Trace Amounts Are Contained In Hemp Seed Oil

Among numerous health great things about hemp seed oil constituents, you can find trace amounts of methyl salicylate. Hemp seed oil’s fatty acid content (omega-3s and omega-6s) is perhaps most obviously as a plus that is nutritional. The oil additionally contains 10-15% fibre, 20-25% protein, and 20-30% carbohydrates.

A bioassay posted in “The Composition of Hemp Seed Oil as well as its prospectivebeing a source that is important of” reported regarding the methyl salicylate content of hemp seed oil. They even reported on the other side things contained in hemp seed oil, such as for example cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids.

To Conclude

Therefore let’s review what we’ve learned hence far:

Methyl salicylate is really an ester that is natural is made naturally or synthetically when you look at the lab it is often removed via steam distillation of wintergreen leaves.

Oil of wintergreen may be the strongest, purest concentration of methyl salicylate.

TRY NOT TO INGEST oil of wintergreen.

Methyl salicylate can be present in over-the-counter items such as for example toothache ointments and muscle tissue discomfort relievers to relieve discomfort and produce a soothing feeling. Additionally, it is sometimes utilized in lower amounts to taste meals and sweets.

Wintergreen oil placed on skin when you look at the right doses can express the exact same level of salicylate present in one single 325 mg aspirin tablet.

Methyl salicylate works efficiently against platelet aggregation—about as much as aspirin does.

Methyl salicylate can be found in hemp seed oil in trace amounts.

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